| Simulator: opencor 2021-10-05 | |
| CPU cores: 1 | |
| RAM: 8 GB | |
| Max time: 20 m |
| Submitted: 2022-04-21 03:27:32 PM | |
| Updated: 2022-04-21 03:28:12 PM | |
Status: Succeeded |
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- Paul R. Shorten
- Paul O’Callaghan
- John B. Davidson
- Tanya K. Soboleva
Model Status
This cellML model is known to run in OpenCell, JSIM and COR to recreate the published results. The units have been checked in COR and they are consistent in as much as they are known to be equivalent. This particular version of the CellML model represents fast twitch muscle.
Model Structure
Abstract: The ability for muscle to repeatedly generate force is limited by fatigue. The cellular mechanisms behind muscle fatigue are complex and potentially include breakdown at many points along the excitation
The original paper reference is cited below:
A mathematical model of fatigue in skeletal muscle force contraction, Paul R. Shorten, Paul OJournal of Muscle Research and Cell Motility, 28, 293-313. PubMed ID: 18080210