" ...
During the acute-stage of spinal cord injury (SCI), the endogenous ability to generate plateaus is lost; however, during the chronic-stage of SCI, plateau potentials reappear with prolonged self-sustained firing that has been implicated in the development of spasticity. In this work, we extend previous modeling studies to systematically investigate the mechanisms underlying the generation of plateau potentials in motoneurons, including the influences of specific ionic currents, the morphological characteristics of the soma and dendrite, and the interactions between persistent inward currents and synaptic input.
..."
The XPP and MATLAB models are used in:
Kurian M, Crook SM, Jung R (2011). Motoneuron model of self-sustained
firing after spinal cord injury. J Comput Neurosci. 2011 Apr 28.
[Epub ahead of print] PMID: 21526348
The two compartment motoneuron model can be run using either MATLAB or
XPP.
Two compartment motoneuron model (MATLAB)
To run the model in MATLAB:
Download and save run_twocomp.m and ramp.m files
Run the run_twocomp file.
It will generate a temp1.mat file which is where all the data values
are saved. The ramp.m file which is used in the run_twocomp.m creates
the figures in the format of Fig. 2 in the paper.
The other figures in the paper can be reproduced by changing the
parameter values and using the appropriate ramp or pulse currents and
plotting windows.
Two compartment motoneuron model (XPP)
To run the model in XPP:
Download and save the twocompart_mnmodel.ode file.
In XPP window run using 'Initialconds' and 'Go'. This should generate
a graph similar to figure 2e:

The data generated can be saved to a .dat file for example write the
generated data as 'test.dat'.
The MATLAB program ramp_xpp.m is used to generate figures in Fig.2
format of the paper using the 'test.dat' file.