| Simulator: xpp 8.0 | |
| CPU cores: 1 | |
| RAM: 8 GB | |
| Max time: 20 m |
| Submitted: 2022-02-28 09:46:16 PM | |
| Updated: 2022-02-28 09:46:53 PM | |
Status: Succeeded |
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This model is a reduced version of a spatially organized respiratory central pattern generation network consisting of four neuronal populations (pre-I, early-I, post-I, and aug-E). In this reduction, each population is represented by a single neuron, in an activity-based framework (which includes the persistent sodium current for the pre-I population). The model includes three sources of external drive and can produce several experimentally observed rhythms.
This is the readme for the model associated with the paper:
Rubin JE, Shevtsova NA, Ermentrout GB, Smith JC, Rybak IA (2009) Multiple rhythmic states in a model of the respiratory central pattern generator. J Neurophysiol 101:2146-65
This models runs under XPP available from http://www.math.pitt.edu/~bard/xpp/xpp.html
After downloading and extracting the archive the program can be started for example under linux by cd'ing to the new folder and typing xppaut rubinetal_resp_cpg.ode
Click on Initialconds -> Go
When complete click on Window/zoom -> (W)indow and then change "X Hi" to 10000 and click OK. Then you should see a graph like:
which is similar to the first trace in Figure 2A from the paper.