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Project
Download File
Open Modeling and Exchange (OMEX)
BIOMD0000000490_url.xml
Systems Biology Markup Language (SBML)
BIOMD0000000490-biopax2.owl
Resource Description Framework XML (RDF-XML)
BIOMD0000000490-biopax3.owl
BIOMD0000000490-matlab.m
MATLAB
BIOMD0000000490-octave.m
BIOMD0000000490.m
BIOMD0000000490.ode
BIOMD0000000490.pdf
Portable Document Format (PDF)
BIOMD0000000490.png
Portable Network Graphics (PNG)
BIOMD0000000490.svg
Scalable Vector Graphics (SVG)
curation_image.png
curation_notes.txt
TEXT
Demin2013_ML10mg.cps
COPASI Markup Language (CopasiML)
Demin2013_ML10mg.sedml
Simulation Experiment Description Markup Language (SED-ML)
Demin2013_ML50mg.cps
Demin2013_ML50mg.sedml
Demin2013_ZL400mg.cps
Demin2013_ZL400mg.sedml
Demin2013_ZL600mg.cps
Demin2013_ZL600mg.sedml
metadata.rdf
OMEX Metadata
Outputs
JavaScript Object Notation (JSON) in BioSimulators simulator schema
Zip of HDF5 and PDF files
Log
JavaScript Object Notation (JSON) in BioSimulators log schema
Balaji M. Agoram & Oleg Demin. Integration not isolation: arguing the case for quantitative and systems pharmacology in drug discovery and development. Drug Discovery Today 16, 23-24 (2011).
O Demin, T Karelina, D Svetlichniy, E Metelkin, G Speshilov, O Demin, D Fairman, PH van der Graaf & BM Agoram. Systems pharmacology models can be used to understand complex pharmacokinetic-pharmacodynamic behavior: an example using 5-lipoxygenase inhibitors. CPT: Pharmacometrics & Systems Pharmacology 2, 9 (2013).
Piet H. van der Graaf & Neil Benson. Systems pharmacology: bridging systems biology and pharmacokinetics-pharmacodynamics (PKPD) in drug discovery and development. Pharmaceutical Research 28, 7 (2011).
Tatiana A Karelina, Kirill V Zhudenkov, Oleg O Demin, Dmitry V Svetlichny, Balaji Agoram, David Fairman & Oleg V Demin. Regulation of leukotriene and 5oxoETE synthesis and the effect of 5-lipoxygenase inhibitors: a mathematical modeling approach. BMC Systems Biology 6 (2012).
Uniform time course
LSODA/LSODAR hybrid method
SBML
SED-ML
COMBINE/OMEX
tellurium 2.2.8
6488f14c6262268786a35f64
BioModels
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